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Today, with the rapid changes in social and living environments, and the diversification of values and lifestyles, there is growing interest in maintaining health through self-care. To address the discomforts felt by each and every one of our consumers, we are developing a wide range of products that utilize life science and interface science, as well as bringing together our technological research capabilities cultivated through the development of fundamental technologies, to develop total health care products and services that enable individuals to practice self-care in order to maintain their health and well-being in a natural and positive way.
A Scientific Approach to Studying the Properties of Hair
Development of Face Care Products Tailored to Skin Condition and Needs
Study of SNPs related to visceral fat reduction effect of lactoferrin
ifia JAPAN 2023
2023/05/19
Ayumi Matsuno
Maltotetraose alleviates chronic itch by inhibiting Substance P-Neurokinin 1 receptor pathway
International Societies for Investigative Dermatology 2023
2023/05/10
Keisuke Yoshida
Relationship between menstrual pain and related disorders and living behavior in working women
The 93rd Annual Meeting of the Japanese Society for Hygiene
2023/03/02
Kanako Yuyama
Young Investigator Excellent Abstract Award
「A study on the association between anti-obesity effects of lactoferrin and genetic variations」
22nd IUNS-ICN International Congress of Nutrition
Young Investigator Excellent Abstract Award
2022/12/6-12/11
Kanae Nakamura
A study on the association between anti-obesity effects of lactoferrin and genetic variations
22nd IUNS-ICN International Congress of Nutrition
2022/12/6-12/11
Kanae Nakamura
Associations between the health benefits of lactoferrin intake and genetic polymorphism
JSoFF2022
2022/10/22-10/23
Daisuke Nishiura
"Japan Lactoferrin Society Award Tomita Award" Study of SNPs related to visceral fat reduction effect of lactoferrin
10th Annual Scientific Meeting "Japan Lactoferrin Society Award Tomita Prize" (Applied category)
2022/10/15
Ayumi Matsuno
Study of SNPs related to visceral fat reduction effect of lactoferrin
Japanese Association for Lactoferrin
2022/10/15
Ayumi Matsuno
Research on the Long-lasting Antibacterial Effects after Using Hand Soap
Japan Oil Chemists' Society Cleaning & Detergent Division
2022/10/11-10/14
Arata Miyachi
Research on the Long-lasting Antibacterial Effects after Using Hand Soap
The Society for Antibacterial and Antifungal Agents, Japan
2022/9/26-9/27
Masashi Tachikawa
Analysis of the mechanism of individual variabilities in the occurrence of menstrual pain by metabolomics (Part 2) - Clinical study using finger-prick blood metabolomics.
The 16th Metabolome Symposium
2022/9/14-9/16
Kanako Yuyama
Analysis of the mechanism of individual variabilities in the occurrence of menstrual pain by metabolomics (Part 1) - Development of finger-prick blood metabolomics.
The 16th Metabolome Symposium
2022/9/14-9/16
Atsushi Sato
Characterization of proton T2 relaxation time of bovine lactoferrin powder before and after high-temperature storage
LWT - Food Science and Technology Volume 163, 15 June 2022, 113521
2022/6/15
Takumi Mitsudome
Study of SNPs related to visceral fat area and BMI reduction effect of lactoferrin
The 76th Annual Meeting of Japan Society of Nutrition and Food Science
2022/6/10-6/12
Ayumi Matsuno
Decreased Frequency of Mental Workload-Induced Subjective Hot Flashes Through Gum Massage: An Open-Label, Self-Controlled Crossover Trial
Women's Health Reports
2022/3/8
Kanako Ichinose
Hair evaluation method based on the actual situation of consumers
The 58th SOCIETY OF COSMETIC CHEMISTS OF JAPAN
2022/2/18
Izumi Oishi
Well-being as a Key Factor for the Creation of Sustainable Local Towns, People, and Workplaces: An Introduction to Well-being Management Initiatives in Ehime, a Region that Sees a Ray of Light in Solving Local Problems
Well-being Expo & Conference 2021 Autumn
2021/11/4-11/5
Takuya Ichinose
Approaches to Visualizing the Effectiveness of Care Focusing on Virus Contact Transmission in the Home
Symposium on Cleaning
2021/10/12-10/15
Keiko Otake
Research on the persistence of antibacterial and antiviral effects by hand washing
Symposium on Cleaning
2021/10/12-10/15
Risako Toki
Development of materials and functional foods for dry mouth, eyes, and skin (dry syndrome)
Health ingredients (Hi) Japan 2021 Food ingredients for Taste (FiT) Japan 2021 Safety & Technology (S-tec) Japan 2021 Food Long Life Japan (LL) 2021
2021/10/6-10/8
Takao Iwai
Proper hand washing, gargling, and disinfection methods and their effects
The 72nd Divisional Meeting of Division of Colloid and Surface Chemistry
2021/9/15-9/21
Yuriko Omoto
Development of skin care detergents with excellent moisturizing and tactile properties
Development and Latest Technology of Moisturizing Cosmetics for Prevention of Rough Skin and Hands
2021/5/28
Michihiro Suzuki
The visceral fat-reducing effect of enteric lactoferrin and its mechanism of action
ifia/HFE JAPAN 2021
2021/5/12-5/14
Tsubasa Yamaguchi
Foot trouble due to sweat and odor and development of corresponding products
FRAGRANCE JOURNAL 2020/3 No.477（Vol.48/No.3）
2021/3/15
Shinichi Nagashima
Washing Cosmetics
Basic Cosmetic Technology Seminar
2021/2/15-2/19
Risako Toki
Technology Introduction of "Nice Slim Essence Lactoferrin" to be delivered to the intestines ～～Visceral Fat Reduction Mechanism and Enteric Coating Technology～
Japanese Association for lactferrin
2020/12/6
Takumi Mitsudome
Ideas for preventing infections in the home and workplace, hand washing and cleaning
The 59th Annual Meeting of the Japan Oil Chemists' Society
2020/11/2-11/7
Yukari Sekine
Application of Anionic Polymers in Cosmetics
COSMETIC STAGE 15(1), 45-50, 2020-10
2020/10/1
Tomoki Sano
Intraoral Approach to Improve the Nasolabial Fold
COSMETIC STAGE 14(6), 39-45, 2020-08
2020/8/1
Yujiro Endo
Washing the skin.
The 119th Annual Meeting of the Japanese Dermatological Association
2020/6/4-6/7
Hotaka Asano
The visceral fat-reducing effect of enteric lactoferrin and its mechanism of action
ifia/HFE JAPAN 2020
2020/4/20-4/22
Takumi Mitsudome
Effect of lactoferrin intestinal solvent on visceral fat reduction
Functional Food Vol.14 No.2 2020
2020
Michiaki Murakoshi、Kanae Nakamura、Tomoji Ono
Enteric-coated lactoferrin decreases abdominal visceral fat in humans: a randomized, double-blind, placebo-controlled, parallel-group study
Jpn Pharmacol Ther 2020 48（7）1179 - 1185
2020
Satoko Sato 1), Mitsuru Nomura 1), Akira Uchiyama 1), Ikuo Fukuhara 2)
1)Research & Development Headquarters, Lion Corporation, 2) Fukuhara Clinic, Eniwa,
Effects of Coexistent Components on the Antiperspirant Action of Aluminium Chlorohydrate
J. Soc. Cosmet. Chem. Jpn. 55（1）: 45‐51(2020)
2020
Tomoki Sano, Wataru Shirae, Yuriko Omoto, Shinichi Nagashima, Atsunori Morigaki, Yasushi Kakizawa, Takaki Ikenishi Research & Development Headquarters, Lion Corporation,
A Study on a Longitudinal Evaluation Method Using Facial Expression Analysis to Capture Emotional Changes during Cosmetics Use
The 18th Conference of the Japanese Society for Cognitive Psychology
Eisuke Inagaki
Rooibos extract, containing eriodictyol-6-C-β-D-glucoside as the active component, stimulate the M3 muscarinic acetylcholine receptor
The 7th International Conference on Food Factors (ICoFF2019)
2019/12/1-12/5
Takao Iwai
Influence of low-molecular-weight aggregates on aggregate growth kinetics and physical properties of solid-state proteins during storage
Eur. J. Pharm. Biopharm. Volume146, Jan 2020, Pages 10-18
2019/11/16
Takumi Mitsudome 1), Mitsutoshi Moribe 1),Yoshiyuki Obayashi 1), Akira Uchiyama 1),, Megumi Aono 1),
1) Research & Development Headquarters, Lion Corporation,
Rooibos extract activates M3 muscarinic acetylcholine receptor and relieves human dryness
Japanese Society of Oral Medicine
2019/9/20-9/23
Takao Iwai
In vivo mechanism study on the dryness relief function of rooibos extract
Japanese Society of Oral Medicine
2019/9/20-9/23
Takao Iwai
Effects of Rooibos (Aspalathus linearis) Extract on Dryness of Mouth, Eye and Skin in Human
The 28th Annual Meeting of the Japanese Society for Sjögren's syndrome
2019/9/13-9/14
Takao Iwai
Novel effects of rooibos extract on tear and saliva secretion mediated by the muscarinic acetylcholine receptor 3 in mice
Journal of Oral Biosciences
Volume 61, Issue 3, September 2019, Pages 179-182
2019/8/7
Rieko Arakaki 1), Aya Ushio 1), Satoru Kisoda 1), Mami Sato 1), Yoshitaka Nakamura 2), Kanako Yuyama 2), Riho Tateyama 2), Satoru Morishita 2), Noriyuki Monoi 2), Yasusei Kudo 1), Naozumi Ishimaru 3)
1)Department of Oral Molecular Pathology Tokushima University Graduate School of Biomedical Sciences, 2)Research & Development Headquarters, Lion Corporation, 3) Department of Oral Molecular Pathology Tokushima University Graduate School of Biomedical Sciences,
Exercise and sports health claims in the system of Foods with Function Claims
The 19th Scientific Meeting of the Japanese Society of Anti-Aging Medicine
2019/6/14-6/16
Mitsuru Nomura
Rooibos (Aspalathus linearis) extract, containing eriodictyol-6-C-β-D-glucoside as the active component, stimulates exocrine glands via the M 3 muscarinic acetylcholine receptor
Journal of Functional Foods
Volume 55, April 2019, Pages 248-254
2019/2/7
Saori Nishimachi a),Takao Iwai a), Yoshitaka Nakamura a), Kanako Yuyama-Masuda a), Takuya Tsutsui a),Noriyuki Monoi a), Akira Uchiyama a),b), Seiji Nakamura c),
a)Research & Development Headquarters, Lion Corporation, b)Division of Oral Health, Growth, and Development, Faculty of Dental Science, Kyushu University, c)Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University,
A new in vitro muscle contraction model and its application for analysis of mTORC1 signaling in combination with contraction and beta-hydroxy-beta-methylbutyrate administration
Bioscience, Biotechnology, and Biochemistry, Volume 83, Issue 10, 2019, Pages 1851–1857
2019/1/4
Satoko Sato 1), Mitsuru Nomura 1), Ikko Yamana 1), Akira Uchiyama 1), Yasuro Furuichi 2), Yasuko Manabe 2), Nobuharu L Fujii 2),
1),Research and Development Headquarters, Lion Corporation, 2),Department of Health Promotion Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University ,
Relationship between female hormone and hair: Development of hair loss treatment
The Journal of Japan Hair Science Association Vol.50,No.4(2018）
2018/12/1
Shunsuke Hiroshima
Quantitative Evaluation of Hair Growth in the Treatment of Hormone Replacement Therapy
The Japan Society for Menopause and Women's Health
2018/11/3-11/4
Yujiro Endo
Effect of lactoferrin on energy expenditure enhancement in reprogrammed functional brown adipocytes
25th International Conference of FFC
2018/10/27-10/28
Kanae Nakamura
Gene expression order attributed to genome reduction and the steady cellular state in Escherichia coli
Front. Microbiol., 20 September 2018
2018/9/20
Bei-Wen Ying 1),2), Kazuma Yama 3)
1)Institute of Biology and Information Science, East China Normal University
2)Faculty of Life and Environmental Sciences, University of Tsukuba
3)Research & Development Headquarters, Lion Corporation
Design of multiscale structured composite particles through mechanical process for fabricating a powder layer with rapid drying properties
2018 SCEJ Autumn Meeting
2018/9/18-9/20
Koichiro Nakamura
Effects of lactoferrin on lipid metabolism in white adipocytes and brown adipocytes
FOOD STYLE21
2018/8/1
Kanae Nakamura
Beta-hydroxy-beta-methylbutyrate (HMB) augments muscle contraction-induced protein synthesis via mTORC1 signaling in cultured L6 myotubes
Experimental Biology 2018
2018/4/21-4/25
Satoko Satoh
Establishment of a new in vitro exercise model and its application to analyze the mechanism of beta-hydroxy-beta-methylbutylate (HMB) on the contraction-induced protein synthesis
The 2018 Annual Meeting of the Japan Society for Bioscience, Biotechnology and Agrochemistry
2018/3/15-3/19
Satoko Satoh
Relationship between female hormone and hair: Development of hair loss treatment
The Journal of Japan Hair Science Association Vol.51,No.1(2019）
2018/3/1
Yujiro Endo
Effects of Rooibos（Aspalathus linearis）Extract on Dryness
of Mouth, Eye and Skin in Human
―A Randomized, Double‒blind, Placebo‒controlled Study―
Jpn Pharmacol Ther 2018 46（6）997 - 1003
2018
Takao Iwai
Anti-Obesity Effect of Lactoferrin; Subgroup Analysis Excluding Subjects with Obese and/or Hyper-LDL Cholesterolemia
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry , Volume 18, Number 1, 2018, pp. 105-109
2018
Tomoji Ono 1), Michiaki Murakoshi 1), Akira Uchiyama 1)
1)Research & Development Headquarters, Lion Corporation
The effects of carotenoids intake for improvement of cognitive functions in healthy adults: a systematic review and meta-analysis of randomized controlled trials
PROSPERO 2018 CRD42018110984
2018
Takahiko Suiko
Bovine lactoferrin promotes energy expenditure via the cAMP-PKA signaling pathway in human reprogrammed brown adipocytes
BioMetals
2018
Kanae Nakamura