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Eating, speaking, laughing—these and other functions of the mouth are crucial to our ability to live comfortably and enjoyably. Lion’s oral science research goes back more than a century. Aiming to improve consumers’ quality of life (QOL), we continue to build on this wealth of knowledge with research in such areas as non-destructive methods of treating dental caries, ways to reduce gingival inflammation based on molecular cytology, and the suppression of bacterial growth using proprietary biofilm models. In recent years, Lion has also partnered with external research institutions to elucidate the influence that conditions in the oral cavity have on the body’s overall health through joint research. By combining a wide range of technologies from in and outside the Lion Group, chiefly in the area of oral science, we strive to create new value through products ranging from those for oral care to food and pharmaceuticals.
Developing Pre-Cavity Detection Technologies
Gum Disease Prevention Technology Development Focused on the Periodontal Tissue
Effect of saliva on suppressing SARS-CoV-2 and influenza virus infection by improving oral hygiene
The 2nd Annual Meeting of the Japan Saliva Care Association Excellent Poster Award
2023/11/26
Taku Iwamoto
Inhibitory Effects of Saliva on SARS-CoV-2 and Influenza Viral Infections by Improving Oral Hygiene
The 71st Annual Meeting of Japanese Association for Dental Research
2023/11/25
Yusuke Kubo
Inhibitory Effects of Saliva on SARS-CoV-2 and Influenza Viral Infections by Improving Oral Hygiene
The 15th International Conference of the Asian Academy of Preventive Dentistry
2023/11/08
Yusuke Kubo
Effects of a new mouthwash on in vitro dental biofilm model
The 15th International Conference of Asian Academy of Preventive Dentistry
2023/11/08
Kim Ryunhee
The effects of hard gummy candy chewing on oral functions in children
The 34th General Meeting of Japanese Society for Mastication Science and Health Promotion
2023/10/28
Kaichi Hayashi
Relationship between crowding and habits in elementary school children in Kuroishi City, Aomori Prefecture
The 65th Annual Meeting of Japanese Association for Oral Biology
2023/09/16
Keishi Sato
Effects of Phellodendron bark extract on periodontal pathogenic bacteria in an in vitro oral microbiome model
The 65th Annual Meeting of Japanese Association for Oral Biology
2023/09/16
Takuma Okuda
Effect of Phellodendron Bark Extract on Bacterial Composition in Oral Biofilm Model
The 65th Annual Meeting of Japanese Association for Oral Biology
2023/09/16
Kanta Ohara
Dysbiosis of Oral Microbiome Persists After Dental Treatment-Induced Remission of Periodontal Disease and Dental Caries
mSystems Vol.8, No.5
2023/09/12
Kazuma Yama
Impact of ORAL FIT, an oral frailty management service, on training continuity and oral function
The 29th Annual Meeting of the Japanese Society of Dysphagia Rehabilitation
2023/09/02
Yukihide Aoyama
Caries prevention effect of toothpaste using fluoride deposition technology
The 70th Congress ORCA 2023
2023/07/05
Chika Akabane
Effect of somatosensory stimulation in the oral cavity by tooth brushing behavior on autonomic nerve activity
Japanese Society of Psychosomatic Dentistry
2023/06/30
Asami Miyajima
Validation of the usefulness of ORAL FIT, an oral frailty management service: A Pilot Study
The 34th Annual Meeting of the Japanese Society of Gerodontology
2023/06/16
Yukihide Aoyama
Decreased Frequency of Subjective Hot Flashes in Daily Life Through Gum Massage in a Pilot Study ―An Open‒label,Self-controlled Trial―
Jpn Pharmacol Ther 2023 51（6）861 - 869
2023/06/01
Kanako Ichinose
Japanese Society of Periodontology Journal Award 2022 "Allantoin, dipotassium glycyrrhizinate, and azulene sulfonate sodium hydrate inhibit gingival inflammation induced by advanced glycation end products via antiglycation effects in vitro"
JSP Journal Award
2023/05/26
Mari Abe-Yutori
Comparison of oral microbiota between oral healthy subjects and periodontal disease patients before and after dental treatment
The 72nd General meeting of Japanese Society for Oral Health
2023/05/19
Kazuma Yama
An in vitro study of the effects of Phellodendron bark extract and berberine chloride on periodontal pathogenic bacteria in the oral microbiome
Journal of Oral Biosciences Volume 65, Issue 1, March 2023, Pages 72-79
2023/03/02
Takuma Okuda
Oxidative stress inhibits endotoxin tolerance and may affect periodontitis
Journal of Dental Research 102(3):331-339
2023/03/02
Tsuguno Yamaguchi
Integrated analysis of the oral and intestinal microbiome and metabolome of elderly people with more than 26 original teeth: a pilot study
Frontiers in Microbiology
2023/10/12
Yuichiro Nishimoto（Metagen, Inc.）
Kazuma Yama（Lion Corporation）
Stain removal efficacy of toothbrush with elastomer-coated bristles
International Association for Dental Research(IADR)
2023/06/21
Phassamon Piyapakorn
Potassium Nitrate and Aluminum Lactate Containing Toothpaste Reduces Dentin Hypersensitivity
International Association for Dental Research(IADR)
2023/06/21
Taiki Suzuki
Plaque Removal Efficacy of New Developed IoT Toothbrush with Brushing Navigation for Children
International Association of Paediatric Dentistry
2023/06/14
Naoshi Kanamaru
Acceleration of toothpaste development using Bayesian optimization method
The 37th Annual Conference of the Japanese Society for Artificial
2023/06/06
Eisuke Inagaki
Development and function of "Check-Up toothbrush standard type", a standard toothbrush for caries care
Dental magazine 185
2023/06/01
Kuniyuki Itose, Naoshi Kanamaru
Validation of the usefulness of introducing dental checkups in the workplace
The 66th Spring Meeting of the Japanese Society of Periodontology
2023/05/26
Yu Yamamoto
Effect of encouragement to see a dentist in occupational dental checkups on periodontal disease and systemic health
The 66th Spring Meeting of the Japanese Society of Periodontology
2023/05/26
Kimura Mitsuo
Safety and plaque removal efficacy of Kid’s toothbrush with bendable/unbreakable neck
2023 Central Interntional Dental Exhibition
2023/05/24
Ryosuke Hachisuka
Building a technical foundation for the development of oral care products
The Japan Society for Analytical Chemistry
2023/05/20
Narumi Fujii
Comparison of oral microbiota before and after dental treatment in healthy and carious patients
The 72nd General meeting of Japanese Society for Oral Health
2023/05/19
Takuya Inokuchi
The relationship between the introduction of dental checkups in the workplace and oral health and productivity
The 72nd General meeting of Japanese Society for Oral Health
2023/05/19
Yu Yamamoto
Effects of chewing hard gummies on oral function in elementary school children
The 61st Annual Conference of the Japanese Society of Pediatric Dentistry
2023/05/18
Keishi Sato
Fluoride and Caries prevention
Tokyo Medical and Dental University
2023/03/15
Chika Akabane
Research on an EIS-type biosensor that detects cortisol in saliva
The 70th JSAP Spring meeting 2023
2023/03/15
Yuki Maruyama
Comparison of oral metabolome profiles of stimulated saliva, unstimulated saliva, and mouth-rinsed water
the 1st Annual Meeting of the Japan Saliva Care Research Association
2022/11/27
Yuki Maruyama
Inhibitory effects of toothpaste ingredients on novel coronavirus (SARS-CoV-2) infection in vitro
the 1st Annual Meeting of the Japan Saliva Care Research Association
2022/11/27
Taku Iwamoto
Nanostructural analysis and age-related changes of apatite particles in human dentin
The 44th Annual Meeting of the Japanese Society of Biomaterials
2022/11/21-11/22
Chika Akabane
Age-related changes in mechanical and esthetics properties in human dentin
The 157th Meeting of the Japanese Society of Conservative Dentistry
2022/11/10-11/11
Yuriko Inomata
An in vitro study of the effect of berberine chloride on periodontal pathogenic bacteria in the oral microbiome
The 9th International Human Microbiome Consortium (IHMC) Congress 2022
2022/11/8-11/10
Daisuke Watai
Comparison of oral microbiome profiles in 18-month-old infants and their parents
The 9th International Human Microbiome Consortium (IHMC) Congress 2022
2022/11/8-11/10
Ryutaro Jo
Trends in detection of high prevalent oral bacteria during the first 60 months of life using a next-generation sequencer
The 9th International Human Microbiome Consortium (IHMC) Congress 2022
2022/11/8-11/10
Kazuma Yama
Establishment of oral metabolome profiling method using mouth-rinsed water by capillary electrophoresis–mass spectrometry
The 42nd Symposium on Capillary Electrophoresis (SCE2022)
2022/10/26-10/28
Yuki Maruyama
Relationship between oral care behavior and cold morbidity in workers
The 81st Annual Meeting of Japanese Society of Public Health
2022/10/7-10/9
Ryutaro Jo
evelopment of EIS biosensors for rapid cortisol determination in saliva
2022 International Conference on Solid State Devices and Materials (SSDM2022)
2022/9/26-9/29
Yuki Maruyama
Rapid measurement of EIS biosensors for detecting cortisol concentration in saliva
The 83rd JSAP Autumn meeting 2022
2022/9/20-9/23
Yuki Maruyama
Evaluation of intra-individual variation of oral metabolites using mouth-rinsed water (2): Analysis of inter- and intra-day variation of fat-soluble metabolites by liquid chromatography-mass spectrometry
The 16th Metabolome Symposium
2022/9/14-9/16
Narumi Fujii
Evaluation of intra-individual variation of oral metabolites using mouth-rinsed water (1): Analysis of inter- and intra-day variation of water-soluble metabolites by capillary electrophoresis–mass spectrometry
The 16th Metabolome Symposium
2022/9/14-9/16
Yuki Maruyama
Antiglycation of periodontitis preventive active ingredients in self-care oral hygiene products
The 65th Autumn Meeting of the Japanese Society of Periodontology
2022/9/2-9/3
Tsuguno Yamaguchi
Phellodendron Bark Extract inhibits osteoclastogenesis by regulation of Nfatc1 gene expression
The 14th Asian Pacific Society of Periodontology Meeting 2022
2022/8/29-8/30
Yu Yamamoto
An in vitro study of effects of Phellodendron Bark Extract on the periodontal pathogenic bacteria in the oral microbiome.
The 14th Asian Pacific Society of Periodontology Meeting 2022
2022/8/29-8/30
Takuma Okuda
The effect of the flavor of children's toothpaste on the tooth-brushing behavior of pre-school children
The 56th Annual Meeting of the Japanese Association for the Study of Taste and Smell
2022/8/22-8/24
Tohru Ohki
The survey of taste sensitivity decrease in healthy subjects:
Relationship between age, taste sensitivity and other factors
The 56th Annual Meeting of the Japanese Association for the Study of Taste and Smell
2022/8/22-8/24
Anna Tsuge
The 23rd (2021) Oils and Fats Technical Paper Excellence Award 「The inhibitory effects of toothpaste and mouthwash ingredients on the cellular infection process of SARS-CoV-2 infection in vitro」
Oil & Fat Industry Kaikan Award
2022/8/22
Taku Iwamoto
Survey of taste sensitivity decrease in healthy subjects: Study on tastesensitivity decrease and the affecting factors in the 20s
The 56th Annual Meeting of the Japanese Association for the Study of Taste and Smell
2022/8/22-8/24
Satoshi Tomeoka
Plaque removal efficacy of bendable/unbreakable safety toothbrush for infant
The 4th International Symposium on Oral Care
2022/7/11
Ryosuke Hachisuka
Comparison of Healthy Versus before/after-Dental Treatment Oral Microbiome
International Association for Dental Research(IADR)
2022/6/20-6/25
Takuya Inokuchi
Effectiveness of the new oral care device for children.
International Association for Dental Research(IADR)
2022/6/20-6/25
Tomonari Kanasugi
Inhibitory Effects of Toothpaste Ingredients on SARS-CoV-2 Infection in vitro
International Association for Dental Research(IADR)
2022/6/20-6/25
Taku Iwamoto
Inhibitory Effects of Toothpaste Ingredients on SARS-CoV-2 Infection in vitro
International Association for Dental Research(IADR)
2022/6/20-6/25
Riho Makino
Virucidal activity of oral care products against enveloped viruses
International Association for Dental Research(IADR)
2022/6/20-6/25
Ryosuke Komatsu
Comparison of Healthy Versus before/after-Dental Treatment Oral Metabolome Profiles
International Association for Dental Research(IADR)
2022/6/20-6/25
Narumi Fujii
Usefulness of Porcine Gingiva for Penetration Tests of Hydrophobic Ingredients
International Association for Dental Research(IADR)
2022/6/20-6/25
Aya Ohkuni
Science behind toothbrush
International Association for Dental Research(IADR)
2022/6/20-6/25
Reona Noda
Plaque removal efficacy of kids’ toothbrush with easily bent neck
International Association for Dental Research(IADR)
2022/6/20-6/25
Sakiho Hayashida
Age-related deterioration of the human dentin
International Association for Dental Research(IADR)
2022/6/20-6/25
Chika Akabane
Study of toothpaste applying fluoride retention and release technology
The 156th Meeting of the Japanese Society of Conservative Dentistry
2022/6/16-7/6
Masashi Fujiki
Inhibitory effects of toothpaste and mouthwash ingredients on SARS-CoV-2 infection in vitro
European Federation of Periodontology 10th
2022/6/15-6/18
Kota Tsutsumi
Toothpaste technology that cares for the supportive tissue of teeth
Dental Magazine 181 SUMMER
2022/6/1
Yu Yamamoto
Examination of fluoride retention technology of toothpaste using fluoride retention and release technology in the oral cavity
The 71st General meeting of Japanese Society for Oral Health
2022/5/13-5/27
Mari Imazaki
Fluoride retention and release technology contributing to self-care of dental caries prevention
The 71st General meeting of Japanese Society for Oral Health
2022/5/13-5/27
Mari Imazaki
Development of EIS type biosensor to detect cortisol in saliva
The 69th JSAP Spring meeting 2022
2022/3/22-3/26
Yuki Maruyama
The relationship between malocclusion and habits in elementary school children in Kuroishi city, Aomori prefecture
The 92nd Annual Meeting of the Japanese Society for Hygiene
2022/3/21-3/23
Keishi Sato
Fluoride retention and release technology contributing to self-care of dental caries prevention
The Japan Dental Show 2021
2022/3/4-3/6
Mari Imazaki
Fluoride retention and release technology contributing to self-care of dental caries prevention
Dental Magazine 180 SPRING
2022/3/1
Ryota Hashimoto
About the development and function of the nursing care toothbrush "Elac Toothbrush 620" that facilitates oral care for care recipients
Dental Magazine 180 SPRING
2022/3/1
Aya Miyazawa, Naoshi Kanamaru
Comparison of oral metabolome profiles of stimulated saliva, unstimulated saliva, and mouth-rinsed water
Scientific Reports 12, Article number: 689 (2022)
2022/1/13
Yuki Maruyama 1), Yuichiro Nishimoto 2), Kouta Umezawa 3), Ryosuke Kawamata 1),Yuko Ichiba 1), KotaTsutsumi 1), Mitsuo Kimura 1), Shinnosuke Murakami 2),4), Yasushi Kakizawa 1),Takashi Kumagai 3), TakujiYamada 2),5) & Shinji Fukuda 2),4),6),7)
1)Research and Development Headquarters, Lion Corporation 2)Metabologenomics, Inc., 3)Hiyoshi Oral Health Clinics,4)Institute for Advanced Biosciences,Keio University,5)Department of Life Science and Technology,6)Gut Environmental Design Group, Kanagawa Institute of Industrial Science and Technology, 7)Transborder Medical Research Center, University of Tsukuba,
Inactivation Effect of Toothpaste on New Coronavirus (SARS-CoV-2) and Its Mechanism
The 80th Annual Meeting of Japanese Society of Public Health
2021/12/21-12/23
Yukari Sekine
A cross-sectional study of relationships between periodontal disease and general health: The Hitachi Oral Healthcare Survey
BMC Oral Health
2021/12/15
Shinsuke Kataoka 1), Mitsuo Kimura 1),Tsuguno Yamaguchi 1), Kenji Egashira 1),Yu Yamamoto 1), Yasushi Koike 1),Yuki Ogawa 1), Chika Fujiharu 2), Toshiko Namai 2), Kanako Taguchi 2), Momoko Takahashi 2), Asami Kameda 2), Tomoka Kasen 2),Asami Hano 2), Konomi Kubota 2),Masayuki Sato 1), Hiroaki Yamaga 1), Kaori Nohara 2), Mikiko Shirasawa 2), Chika Sekine 2), Maki Fukuda 2), Arisa Aoki 2),Yurina Takeuchi 2), Misaki Mugiyama 2), Kenta Mori 4), Keigo Sawada 4) Yoichiro Kashiwagi 4), Masahiro Kitamura 4), Takeshi Hayashi 3),Tohru Nakagawa 3), Shinya Murakami 4)
1)Research & Development Head Quarters, LION Corporation,2)The LION Foundation for Dental Health (Public Interest Incorporated Foundation), 3)Hitachi Health Care Center, Hitachi Limited,4)Faculty of Dentistry, Osaka University,
Investigation of a novel technique for controlling the retention and sustained release of fluoride in the oral cavity
The 155th Meeting of the Japanese Society of Conservative Dentistry
2021/10/28-11/10
Masakazu Ono
Why Safety Toothbrushes That Don't Bend or Wiggle Can Brush Without Breaking ～The secret behind the toothbrush was born out of the desire to prevent children's throat-piercing accidents.
The 36th Conference of the Japanese Society of Pediatric Dentistry
2021/10/17-10/23
Ryosuke Hachisuka
Analysis of the effect of active ingredients of medicated toothpaste on RANKL-induced osteoclast differentiation
The 64th Autumn Meeting of the Japanese Society of Periodontology
2021/10/15-10/16
Yu Yamamoto
Analysis of Major Oral Bacterial Changes from Birth to 36 Months of Age Using Next Generation Sequencers
The 63rd Annual Meeting of Japanese Association for Oral Biology
2021/10/9-10/11
Kazuma Yama
Inhibitory effects of toothpaste and mouthwash ingredients on SARS CoV 2 priming protease TMPRSS2
The 63rd Annual Meeting of Japanese Association for Oral Biology
2021/10/9-10/11
Riho Makino
Inhibitory effects of toothpaste and mouthwash ingredients on
the interaction between S-protein of SARS-CoV-2 and ACE2
The 63rd Annual Meeting of Japanese Association for Oral Biology
2021/10/9-10/11
Mari Yutori
The inhibitory effects of toothpaste and mouthwash ingredients on SARS-CoV-2 spike protein-ACE2 interaction, and TMPRSS2 protease activity in vitro
The 14th International Conference of Asian Academy of Preventive Dentistry
2021/10/1-10/3
Taku Iwamoto
The Usefulness of an Oral-Health Promotion Program on Japanese Working-Age Population: A Pilot Study.
The 14th International Conference of Asian Academy of Preventive Dentistry
2021/10/1-10/3
Yukihide Aoyama
Oral care product flavors may prevent respiratory tract infections through promoting airway mucosal clearance
The 14th International Conference of Asian Academy of Preventive Dentistry
2021/10/1-10/3
Yasushi Koike
Potential role of oral care practices in preventing SARS-CoV-2 infection in the era of the “new normal”
The 14th International Conference of Asian Academy of Preventive Dentistry
2021/10/1-10/3
Kota Tsutsumi
The inhibitory effects of toothpaste and mouthwash ingredients on the interaction between the SARS-CoV-2 spike protein and ACE2, and the protease activity of TMPRSS2, in vitro
PLOS ONE 2021; 16(9): e0257705.
2021/9/17
Riho Tateyama-Makino 1), Mari Abe-Yutori 1), Taku Iwamoto 1), Kota Tsutsumi 1), Motonori Tsuji 2) ,Satoru Morishita 1), Kei Kurita 1), Yukio Yamamoto 1), Eiji Nishinaga 1),Keiichi Tsukinoki 3)
1)Research & Development Headquarters, Lion Corporation, 2)Institute of Molecular Function
3)Division of Environmental Pathology, Department of Oral
Science, Kanagawa Dental University
Material design of intelligent plastic products with sound generation function due to snap-through buckling
2021 Eng. Res. Express 3 015006
2021/5/11
Ryosuke Hachisuka1),2), Reona Noda 2), Masayuki Yamaguchi 1)
1)School of Materials Science, Japan Advanced Institute of Science and Technology, 2) Research & Development Headquarters,Lion Corporation,
Survey on oral care habits and halitosis among general community residents
The 18th Annual Meeting of the Japanese Society of Oral Care
2021/4/17-4/18
Chiyoko Uchiyama
Inhibitory effects of toothpaste and mouthwash ingredients on the interaction between Sprotein of SARS-CoV-2 and ACE2
The 101st CSJ Annual Meeting (2021）
2021/3/19-3/21
Mari Yutori
The physiological TMPRSS2 inhibitor HAI-2 alleviates SARS-CoV-2 infection
The 101st CSJ Annual Meeting (2021）
2021/3/19-3/21
Riho Makino
The effect of aging on the nanostructure of murine alveolar bone and dentin
Journal of Bone and Mineral Metabolism volume 39, pages757–768 (2021)
2021/3/11
Chika Akabane 1),2), Silvia Pabisch 2) , Wolfgang Wagermaier 2), Andreas Roschger 2),3) , Norio Tobori 1), Tomomichi Okano 1). Shinya Murakami 4), Peter Fratzl 2), Richard Weinkamer 2)
1)Research & Development Headquarters, Lion Corporation, 2)Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany, 3)Department of Chemistry and Physics of Materials, Paris-Lodron-University of Salzburg, Salzburg, Austria, 4)Department of Periodontology, Graduate School of Dentistry, Osaka University, Osaka, Japan
Comparison of oral microbiome profiles in 18-month-old infants and their parents
Scientific Reports 11, Article number: 861 (2021)
2020/1/13
Ryutaro Jo, Kazuma Yama, Yuto Aita, Kota Tsutsumi, Chikako Ishihara,Masato Maruyama, Eiji Nishinaga & Ken-ichiro Shibasaki
Research and Development Headquarters, Lion Corporation,
Basic study on staining and removal of dentin by various beverages
The 70th General meeting of Japanese Society for Oral Health
2021/5/27-6/10
Ayaka Iwasaki
Development of Clinica NEXT STAGE toothbrush
Packaging Technology
2020/12/1
Reona Noda，Shizuka Kawasaki，Ryosuke Hachisuka
Oral checkup with health guidance promoted changes in oral health behavior of examinees in a workplace.
The 79th Annual Meeting of Japanese Society of Public Health
2020/10/20-10/22
Koichiro Hayashi
The Effect of Bile Salts/Phospholipid Mixed Solutions on the Morphology of Giant Unilamellar Vesicles
The 31st General Scientific Meeting of Japan Academy of Esthetic Dentistry
202010/3-10/4
Ryota Hashimoto
Development of "RePERO", an application to support breath care
The 71st Divisional Meeting of Division of Colloid and Surface Chemistry
2020/9/13-9/16
Kengo Oka
Self-care products：Functions and usefulness of fluoride toothpaste
Society of dental Prctice administration
2020/9/13
Ken-ichiro Shibasaki
Reachability beyond the last molar and dental plaque removal ability of markedly thin-headed, slim-necked toothbrushes
International Conference on Oral Protection Science
2020/7/21-7/24
Yuya Kimoto
Effects of aluminum lactate and cationic cellulose containing Tooth Paste on sealing dentinal tubules
The 152nd Meeting of the Japanese Society of Conservative Dentistry
2020/6/11-6/12
Rika Oda
Effects of Phellodendron Bark Extract on RANKL-induced osteoclastogenesis
The 63rd Spring Meeting of the Japanese Society of Periodontology
2020/5/29-5/30
Kenji Egashira
A Study on the Brushing Skill of a New Children's IoT Toothbrush Featuring Tooth Brushing Navigation
The 58th Annual Conference of the Japanese Society of Pediatric Dentistry
2020/5/20-5/21
Mai Satake
Gingiva-specific Collagen Gene Regulation by Oxidative Stress
International Association for Dental Research(IADR)
2020/3/18-3/21
Tsuguno Yamaguchi
Fluoride and Caries Prevention
Tokyo Medical and Dental University
2020/3/11
Eiji Nishinaga
Inhibitory effects of pyrrolidone carboxylic acid on dentin demineralization and collagen degradation
THE JAPANESE JOURNAL OF CONSERVATIVE DENTISTRY(Jpn J Conserv Dent)
2020/1/7
Shiori Ishii, Mari Imazaki, Sara Isurugi, Haruhiko Fujikawa, Yasushi Fukuda, Eiji Nishinaga
Japan Institute of invention and innovation
No.：6591988（Toothbrushes that can limit damage to the user's mouth）
Japan Institute of Invention and Innovation
2020/11/12
Ryosuke Haschisuka
Asian Pacific Society of Periodontology Meeting 2019 Poster presentation competition Lab research 1st Prize
「Effects of pyrrolidone carboxylic acid on dentin collagen degradation and demineralization」
The 13th Asian Pacific Society of Periodontology Meeting 2019
2019/9/28-9/29
Shiori Ishii
Comparison of oral bacterial profiles in stimulated and unstimulated saliva, tongue, and mouth-rinsed water.
Scientific Reports 9, Article number: 16124 (2019)
2019/11/6
Ryutaro Jo 1), Yuichiro Nishimoto 2), Kouta Umezawa 3), Kazuma Yama 1), Yuto Aita 1), Yuko Ichiba 1), Shinnosuke Murakami 2),4), Yasushi Kakizawa 1), Takashi Kumagai 3), TakujiYamada 2),5),6) Shinji Fukuda2),4),6),7),8)
1)Research and Development Headquarters, 2)Metabologenomics, Inc.,3)Hiyoshi Oral Health Clinics. ,4)Institute for Advanced Biosciences, Keio University,5)Department of Life Science and Technology, Tokyo Institute of Technology, 6)PRESTO, Japan Science and Technology Agency,8)Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, 8)Transborder Medical Research Center, University of Tsukuba,
Direct-to-consumer genetic testing data identified the possible risk markers associated with the oral cavity health among Japanese subjects.
American Society of Human Genetics 2019 Annual Meeting
2019/10/15-10/19
Satoshi Morishita
Improvement of Mechanical Toughness of Polypropylene by Laminating with Elastomer
Journal of Polymer Research volume 26, Article number: 246 (2019)
2019/9/12
Ryosuke Hachisuka 1)2), Toshiaki Kobayashi 3), Masayuki Yamaguchi 2)
1)School of Materials Science, Japan Advanced Institute of Science and Technology,2)Research & Development Headquarters, Lion Corporation, 3)The Lion Foundation for Dental Health, (Public Interest Incorporated Foundation)
A New Method to Speculate Halitosis Level Using Machine Learning
International Association for Dental Research (IADR)
2019/6/19-6/22
Chiaki Michibayashi
Lactoferrin Promotes Proliferation and Wound Healing of Human Gingival Fibroblasts―in vitro study
Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 2019 Volume61 Issue1 Pages 18-27
2019/3/29
Naho Suzuki
The Journal of Japanese Society of Periodontology, 2019 Journal Award
「Lactoferrin Promotes Proliferation and Wound Healing of Human Gingival Fibroblasts -in vitro study」
Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 2019 Volume61 Issue1 Pages 18-27
2019/3/29
Naho Suzuki
A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis
Scientific Reports 9, Article number: 3559 (2019)
2019/3/5
Takuya Hayakawa 1), Shizuka Kawasaki 1), Yutaka Hirayama 1),Takuya Tsutsui 1), Eiji Sugiyama 2), Kiyo Adachi 1), Ryo Kon 1), Makoto Suematsu 2), Yuki Sugiura 2)
1)Research & Development Headquarters, Lion Corporation, 2)Department of Biochemistry, Keio University School of Medicine,
Importance of approaches to the host's defense mechanism in the prevention of periodontal disease and the effects of vitamin E
The 149th Meeting of the Japanese Society of Conservative Dentistry
2018/11/1
Mari Yutori
Effects of copper gluconate on oral malodor
The 61st Autumn Meeting of the Japanese Society of Periodontology
2018/10/26-10/27
Masato Takahashi
The wound healing effect of vitamin-E on human gingival fibroblasts
The 61st Autumn Meeting of the Japanese Society of Periodontology
2018/10/26-10/27
Mari Yutori
Evaluation of vitamin-E permeability using human three-dimensional culture epidermis model
The 61st Autumn Meeting of the Japanese Society of Periodontology
2018/10/26-10/27
Kazuaki Kojima
Technologies supporting oral care products
The 60th Annual Meeting of Japanese Association for Oral Biology
2018/9/5-9/7
Mari Yutori
Effects of sodium polyacrylate on periodontal disease biofilm in vitro
The 61st Spring Meeting of the Japanese Society of Periodontology
2018/6/1-6/2
Yusuke Kawanobe
THE 2nd INTERNATIONAL ORAL CARE TECHNICAL SEMINAR
Excellent scientific papers First Class
「Decomposition and removal of dental model plaque by using toothpaste containing dextranase」
THE 2nd INTERNATIONAL ORAL CARE TECHNICAL SEMINAR
2018/4/12
Yuko Aoki 1), Gotaro Izumi 1), Yasuo Nomura 1), Ken-ichiro Shibasaki 1), 刘婧 2), 李德豹 2), 安丰宝 2) ,郑苏江 3)
1)Lion Corporation
2)獅王日用化工（青島）有限公司
3)中国科学院理化技術研究所
Analysis of oral microbiome formation process in infancy
The 91st Anuual Meeting of Japanese Society for Bacteriology
2018/3/27-3/29
Ryutaro Jo